Endocannabinoid System 101

Endocannabinoid System 101

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The endocannabinoid system (ECS) is a biological system composed of endocannabinoids, which are endogenous lipid-based retrograde neurotransmitters that bind to cannabinoid receptors (CBRs), and cannabinoid receptor proteins that are expressed throughout the vertebrate central nervous system (including the brain) and peripheral nervous system. 

The endocannabinoid system is a molecular system responsible for regulating and balancing many processes in the body, including immune response, communication between cells, appetite and metabolism, memory, and more.

Until recently, scientists had identified cannabinoids in hemp. Current research, however, has found cannabinoids in many plants, including clove, black pepperEchinacea, broccoli, ginseng, and carrots.

Endocannabinoids, also called endogenous cannabinoids, are molecules made by your body. They're similar to cannabinoids, but they're produced by your body. Experts have identified two key endocannabinoids so far: [CB1] anandamide (AEA) and [CB2] 2-arachidonoylglyerol (2-AG).

Many industry operators find the 118 minor cannabinoids present in cannabis, particularly compelling as they represent an untapped medical arsenal, with early research suggesting minor cannabinoids to have as much if not more potential in nutrition and wellness as Cannabidiol (CBD) and Tetrahydrocannabinol (THC). Unlike CBD and THC, minor cannabinoids are not under international drug schedules, and are not considered controlled substances in the USA.

Recent scientific research has indicated that both cannabinoids and terpenes may be able to be used as antiviral drugs.

Cannabidivarin (CBDV) [discovered in 1969] has been linked to alleviating many conditions, including epilepsy and muscular dystrophy.

Cannabinol (CBN) may be used effectively as a sleep aid or sedative, shown to help regulate the immune system and works to relieve the pain and inflammation caused by several conditions, including arthritis and Crohn's disease. 

Cannabigerovarin (CBGV) may play a role in controlling or reducing proliferation of cancer, pain, nausea,
and inflammation.

Cannabichromene (CBC), may play roles in neurogenesis, and seems to have many of the same properties as CBD in regards to reducing or controlling inflammation, and in potentially battling cancer.

Cannabichromevarin (CBCV) [discovered in 1973] holds the potential to relieve seizures in infants and children. The researchers of the Regents of the University of California hold a patent with regards to an anticonvulsant drug for children dealing with seizures. 

Lastly Tetrahydrocannabivarin (THCV), nicknamed the “diet cannabinoid” for potentially curbing one’s appetite, THCV has been linked with promise in treating both Alzheimer’s and Parkinson’s diseases.

Given the compelling promise shown by the few cannabinoids investigated to date, the potential for further discoveries of medically impactful cannabinoids seems immense. There remain many other cannabinoids which have not been investigated, for which there is no available data toward potential medical or wellness utility.

 

This website is not intended to provide medical information and does not claim to cure or treat any disease. Always consult your doctor about health concerns or medical advice. These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. The efficacy of these products have not been confirmed by FDA-approved research. 
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